Selected Publications

Van Wesenbeeck L, Odgren PR, Coxon FP, Frattini A, Moens P, Perdu B, MacKay CA, Van Hul E, Timmermans J-P, Vanhoenacker F, Jacobs R, Peruzzi B, Teti A, Helfrich MH, Rogers MJ, Villa A and Van Hul W. PLEKHM1 is involved in osteoclastic vesicular transport and mutations in this gene cause osteopetrosis in the incisors absent rat and human.J. Clin Invest. 2007 (in press).

Thompson K, Rojas J and Rogers MJ. Alkylamines cause Vgamma9Vdelta2-T cell activation and proliferation by inhibiting the mevalonate pathway Blood 2006; 107: 651-654.

Thompson K and Rogers MJ. Statins prevent bisphosphonate-induced gamma, delta-T cell proliferation and activation in vitro. J. Bone Miner. Res. 2004; 19: 278-288.

Coxon FP, Helfrich MH, Larijani B, Muzylak M, Dunford JE, Marshall D, McKinnon AD, Nesbitt SA, Horton MA, Seabra MC, Ebetino FH and Rogers MJ. Identification of a novel phosphonocarboxylate inhibitor of Rab geranylgeranyl transferase that specifically prevents Rab prenylation in osteoclasts and macrophages. J. Biol. Chem. 2001; 276: 48213-48222.

Frith JC, Monkkonen J, Auriola S and Rogers MJ. The molecular mechanism of action of the antiresorptive and antiinflammatory drug clodronate: evidence for the formation in vivo of a metabolite that inhibits bone resorption and causes osteoclast and macrophage apoptosis. Arth. Rheum. 2001; 44: 2201-2211.