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Institute of Biomedical Research
Medical School
Wolffson Drive
BIRMINGHAM
Warwickshire
B15 2TT
Research Goals
Chromatin is a key regulator of gene transcription, DNA replication and repair. Dysregulation of these processes often leads to cancer. We will investigate how three mechanisms of altering chromatin structure: ATP-dependent chromatin remodelling, post-translational histone modification, and histone variant incorporation cooperate to regulate gene expression in a Drosophila cancer model.
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