Selected Publications
Carroll JS, Meyer CA, Song S, Li W, Brodsky AS, Geistlinger TR, Eeckhoute J, Keeton EK, Fertuck KC, Hall GF, Wang Q, Bekiranov S, Sementchenko V, Fox EA, Silver PA, Gingeras TR, Liu XS and Brown M. Genome-wide analysis of estrogen receptor binding sites. Nat Genetics 2006; 38: 1289-1297. PubMed
Eeckhoute J, Carroll JS, Geistlinger TR, Torres-Arzayus MI and Brown M. A cell-type specific transcriptional network required for estrogen regulation of cyclin D1 and cell cycle progression in breast cancer. Genes Dev 2006; 20: 2513-2526. PubMed Full text
Carroll DK, Carroll JS, Leong C-O, Cheng F, Brown M, Mills AA, Brugge JS and Ellisen LW. p63 regulates an adhesion programme and cell survival in epithelial cells. Nat Cell Biol 2006; 8: 551-561. PubMed
Carroll JS, Liu XS, Brodsky AS, Meyer CA, Li W, Szary AJ, Eeckhoute J, Shao W, Hestermann EV, Geistlinger TR, Fox EA, Silver PA and Brown M. Chromosome-wide mapping of Estrogen Receptor binding reveals long-range regulation requiring the Forkhead protein FoxA1. Cell 2005; 122: 33-43. PubMed
Wang Q, Carroll JS and Brown M. Spacial and temporal recruitment of Androgen Receptor and its coactivators leads to chromosomal looping and polymerase tracking. Mol Cell 2005; 19: 631-642. PubMed
Primary Research Publications
2008
Bhat-Nakshatri P, Wang G, Appaiah H, Luktuke N, Carroll JS, Geistlinger TR, Brown M, Badve S, Liu Y, Nakshatri H. AKT alters genome-wide estrogen receptor alpha binding and impacts estrogen signalling in breast cancer. Molecular and Cellular Biology 2008; 28:7487-503
Holmes KA, Song JS, Liu XS, Brown M, Carroll JS. Nkx3-1 and LEF-1 function as transcriptional inhibitors of estrogen receptor activity. Cancer Research 2008; 68:7380-5
Hurtado A, Holmes KA, Geistlinger TR, Hutcheson IR, Nicholson RI, Brown M, Jiang J, Howat WJ, Ali S, Carroll JS. Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen. Nature 2008; 456:663-6
Johnson DS, Li W, Gordon DB, Bhattacharjee A, Curry B, Ghosh J, Brizuela L, Carroll JS, Brown M, Flicek P, Koch CM, Dunham I, Bieda M, Xu X, Farnham PJ, Kapranov P, Nix DA, Gingeras TR, Zhang X, Holster H, Jiang N, Green R, Song JS, McCuine SA, Anton E, Nguyen L, Trinklein ND, Ye Z, Ching K, Hawkins D, Ren B, Scacheri PC, Rozowsky J, Karpikov A, Euskirchen G, Weissman S, Gerstein M, Snyder M, Yang A, Moqtaderi Z, Hirsch H, Shulha HP, Fu Y, Weng Z, Struhl K, Myers RM, Lieb JD, Liu XS. Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets. Genome Research 2008; 18:393-403
Krum SA, Miranda-Carboni GA, Hauschka PV, Carroll JS, Lane TF, Freedman LP, Brown M. Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival. EMBO Journal 2008; 27: 535-45
Krum SA, Miranda-Carboni GA, Lupien M, Eeckhoute J, Carroll JS, Brown M. Unique ER alpha cistromes control cell type-specific gene regulation. Molecular Endocrinology 2008; 22:2393-406
Li W, Carroll JS, Brown, M, Liu S. xMAN: extreme MApping of oligonucleotides. BMC Genomics 2008; 9 Suppl 1:S20
Lupien M, Eeckhoute J, Meyer CA, Wang Q, Zhang Y, Li W, Carroll JS, Liu XS, Brown M. FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription. Cell 2008; 132:958-70
2007
Eeckhoute J, Keeton EK, Lupien M, Krum SA, Carroll JS, Brown M. Positive cross-regulatory loop ties GATA-3 to estrogen receptor alpha expression in breast cancer. Cancer Research 2007; 67:6477-83.
Schmelzle T, Mailleux AA, Overholter M, Carroll JS, Solimini NL, Lightcap ER, Veiby OP, Brugge JS. Functional role and oncogene-regulated expression of the BH3-only proapoptotic factor Bmf in mammary epithelial anoikis. PNAS 2007; 104:3787-92.
Wang Q, Li W, Liu XS, Carroll JS, Janne OA, Chinnaiyan AM, Pienta KJ, Brown M. A transcriptional regulatory network governs prostate cancer growth and survival. Molecular Cell 2007; 27:380-392.
Other Publications
Dietz SC, Carroll JS. Interrogating the genome to understand oestrogen-receptor-mediated transcription. Expert Reviews in Molecular Medicine 2008; 10:e10
Green KA, Carroll JS. Opinion - Oestrogen-receptor-mediated transcription and the influence of co-factors and chromatin state. Nat Rev Cancer 2007; 7(9):713-722
