Adele Murrell

Epigenetics and Imprinting
Cancer Research UK Cambridge Research Institute
Li Ka Shing Centre
Robinson Way
Cambridge
CB2 0RE

Research Goals
The term epigenetic refers to mitotically stable changes in gene expression that cannot be attributed to changes in DNA sequence. Genomic imprinting is an epigenetic phenomenon whereby only one parental allele is expressed. Our goal is to determine the extent to which genetic and epigenetic variation within the imprinted Insulin-like growth factor 2 (IGF2) gene is associated with an innate susceptibility to cancer and to unravel the molecular mechanisms that lead to loss of imprinting.

Qualifications and Personal History
1995 - PhD, Department of Haematology, Cambridge University
1996-2004 - Post-doctoral research in Genomic Imprinting and Epigenetics, the Babraham Institute and Sanger Institute, Cambridge
2005 to present - Senior Cancer Research Fellow, Department of Oncology, University of Cambridge

Joined the Cancer Research UK Cambridge Research Institute in summer 2006.