Selected Publications

Odom DT, Dowell RD, Jacobsen ES, Nekludova L, Rolfe PA, Danford TW, Gifford DK, Fraenkel E, Bell GI and Young RA. Core transcriptional regulatory circuitry in human hepatocytes. Mol Syst Biol 2006, doi:10.1038/msb4100059. PubMed

Scacheri PC, Davis S, Odom DT, Crawford GE, Perkins S, Halawi MJ, Agarwal SK, Marx SJ, Spiegel AM, Meltzer PS and Collins FS. Genome-wide analysis of Menin biding provides insights to MEN1 tumorigenesis. PLoS Genetics 2006; 2: e51. PubMed PDF (in UKPMC)

Palomero T, Odom DT, O'Neil J, Ferrando AA, Margolin A, Neuberg DS, Winter SS, Larson RS, Li W, Liu XS, Young RA and Look AT. Transcriptional regulatory networks downstream of TAL1/ SCL in T-cell acute lymphoblastic leukemia. Blood, e-publ 18 Apr 2006 doi:10.1182/blood-2005-08-3482. PubMed

Zhang X, Odom DT, Koo S-H, Conkright MD, Canettieri G, Best J, Chen H, Jenner R, Herbolsheimer E, Jacobsen E, Kadam S, Ecker JR, Emerson B, Hogenesch JB, Unterman T, Young RA and Montminy M. Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues. Proc Natl Acad Sci USA 2005; 102: 4459-4463. PubMed PDF (in UKPMC)

Odom DT, Zizlsperger N, Gordon DB, Bell GW, Rinaldi NJ, Murray HL, Volkert TL, Schreiber J, Rolfe PA, Gifford DK, Fraenkel E, Bell GI and Young RA. Control of pancreas and liver gene expression by HNF transcription factors. Science 2004; 303: 1378-1381. PubMed

Primary Research Publications

2008

Schmidt D, Stark R, Wilson MD, Brown GD, Odom DT. Genome-scale validation of deep-sequencing libraries. PLoS ONE 2008; 3:e3713

Wilson MD, Barbosa-Morais NL, Schmidt D, Conboy CM, Vanes L, Tybulewicz VL, Fisher EM, Tavar&ecute; S, Odom DT. Species-specific transcription in mice carrying human chromosome 21. Science 2008; 322:434-8

2007

Conboy CM, Spyrou C, Thorne NP, Wade EJ, Barbosa-Morais NL, Wilson MD, Bhattacharjee A, Young RA, Tavaré S, Lees JA, Odom DT. Cell cycle genes are the evolutionarily conserved targets of the E2F4 transcription factor. PLoS ONE 2007; 2:e1061.

Odom DT, Dowell RD, Jacobsen ES, Gordon W, Danford TW, MacIsaac KD, Rolfe PA, Conboy CM, Gifford DK, Fraenkel E. Tissue-specific transcriptional regulation has diverged significantly between human and mouse. Nat Genet 2007; 39(6):730-732

2006

Palomero T, Lim WK, Odom DT, Sulis ML, Real PJ, Margolin A, Barnes KC, O'Neil J, Neuberg D, Weng AP, Aster JC, Sigaux F, Soulier J, Look AT, Young RA, Califano A, Ferrando AA. NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth. Proc Natl Acad Sci U S A 2006; 103(48):18261-18266

Wardle FC, Odom DT, Bell GW, Yuan BB, Danford TW, Wiellette EL, Herbolsheimer E, Sive HL, Young RA, Smith JC. Zebrafish promoter microarrays identify actively transcribed embryonic genes. Genome Biol 2006; 7(8):Article 71