Selected Publications
Pharoah PDP, Dunning AM, Ponder BAJ and Easton DF. Association studies for finding cancer-susceptibility genetic variants. Nature Rev Cancer 2004; 4: 850-860. PubMed
Cranston AN and Ponder BAJ. Modulation of medullary thyroid carcinoma penetrance suggests the presence of modifier genes in a RET transgenic mouse model. Cancer Res 2003; 63: 4777-4780. PubMed
Pharoah PDP, Antoniou A, Bobrow M, Zimmern RL, Easton DF and Ponder BAJ. Polygenic susceptibility to breast cancer and implications for prevention. Nature Genetics 2002; 31: 33-36. PubMed
Pharoah PD, Antoniou AC, Easton DF, Ponder BAJ. Polygenes, risk prediction, and targeted prevention of breast cancer. New England Journal of Medicine 2008;358(26):2796-803.PubMed
Easton DF, Pooley KA, Dunning AM, Pharoah PD, Thompson D, Ballinger DG, Struewing JP, Morrison J, Field H, Ponder BAJ, et al. Genome-wide association study identifies novel breast cancer susceptibility loci. Nature 2007; 447:1087-1093. PubMed
Cox A, Dunning AM, Garcia-Closas M, Balasubramanian S, Reed MWR, Pooley KA, Scollen S, Baynes C, Ponder BAJ, Chanock S, et al. A common coding variant in CASP8 is associated with breast cancer risk. Nature Genetics 2007; 39:352-358. PubMed
Primary Research Publications
2008
Barber ME, Murrell A, Ito Y, Maia A-T, Hyland S, Oliveira C, Save V, Carneiro F, Paterson AL, Grehan N, Dwerryhouse S, Lao-Sirieix P, Caldas C, Fitzgerald RC. Mechanisms and sequelae of E-cadherin silencing in hereditary diffuse gastric cancer. The Journal of Pathology 2008; 216:295-306
Barnett GC, Shah M, Redman K, Easton DF, Ponder BAJ, Pharoah PD. Risk factors for the incidence of breast cancer: do they affect survival from the disease? Journal of Clinical Oncology 2008; 26:3310-6
Driver KE, Song H, Lesueur F, Ahmed S, Barbosa-Morais NL, Tyrer J, Ponder BAJ, Easton DF, Pharoah PD, Dunning AM; for the SEARCH Team. Association of single-nucleotide polymorphisms in the Cell Cycle genes with breast cancer in the British population. Carcinogenesis 2008; 29:333-41
Garcia-Closas M, Hall P, Nevanlinna H, Pooley K, Morrison J, Richesson DA, Bojesen SE, Nordestgaard BG, Axelsson CK, Arias JI, Milne RL, Ribas G, Gonz´lez-Neira A, Benítez J, Zamora P, Brauch H, Justenhoven C, Hamann U, Ko YD, Bruening T, Haas S, Dörk T, Schürmann P, Hillemanns P, Bogdanova N, Bremer M, Karstens JH, Fagerholm R, Aaltonen K, Aittomäki K, von Smitten K, Blomqvist C, Mannermaa A, Uusitupa M, Eskelinen M, Tengström M, Kosma VM, Kataja V, Chenevix-Trench G, Spurdle AB, Beesley J, Chen X, Australian Ovarian Cancer Management Group, Kathleen Cuningham Foundation Consortium For Research Into Familial Breast Cancer, Devilee P, van Asperen CJ, Jacobi CE, Tollenaar RA, Huijts PE, Klijn JG, Chang-Claude J, Kropp S, Slanger T, Flesch-Janys D, Mutschelknauss E, Salazar R, Wang-Gohrke S, Couch F, Goode EL, Olson JE, Vachon C, Fredericksen ZS, Giles GG, Baglietto L, Severi G, Hopper JL, English DR, Southey MC, Haiman CA, Henderson BE, Kolonel LN, Le Marchand L, Stram DO, Hunter DJ, Hankinson SE, Cox DG, Tamimi R, Kraft P, Sherman ME, Chanock SJ, Lissowska J, Brinton LA, Peplonska B, Klijn JG, Hooning MJ, Meijers-Heijboer H, Collee JM, van den Ouweland A, Uitterlinden AG, Liu J, Lin LY, Yuqing L, Humphreys K, Czene K, Cox A, Balasubramanian SP, Cross SS, Reed MW, Blows F, Driver K, Dunning A, Tyrer J, Ponder BA, Sangrajrang S, Brennan P, McKay J, Odefrey F, Gabrieau V, Sigurdson A, Doody M, Struewing JP, Alexander B, Easton DF, Pharoah PD. Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics. PLoS Genetics 2008; 4:e1000054
Ghoussaini M, Song H, Koessler T, Al Olama AA, Kote-Jarai Z, Driver KE, Pooley KA, Ramus SJ, Kjaer SK, Hogdall E, Dicioccio RA, Whittemore AS, Gayther SA, Giles GG, Guy M, Edwards SM, Morrison J, Donovan JL, Hamdy FC, Dearnaley DP, Ardern-Jones AT, Hall AL, O'Brien LT, Gehr-Swain BN, Wilkinson RA, Brown PM, Hopper JL, Neal DE, Pharoah PD, Ponder BAJ, Eeles RA, Easton DF, Dunning AM; for the UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology and the UK ProtecT Study Collaborators. Multiple loci with different cancer specificities within the 8q24 gene desert. Journal of the National Cancer Institute 2008; 100:962-6
Ito Y, Koessler T, Ibrahim AE, Rai S, Vowler SL, Abu-Amero S, Silva AL, Maia A-T, Huddleston JE, Uribe-Lewis S, Woodfine K, Jagodic M, Nativio R, Dunning A, Moore G, Klenova E, Bingham S, Pharoah PD, Brenton JD, Beck S, Sandhu MS, Murrell A. Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer. Human Molecular Genetics 2008; 17:2633-43
Kalmyrzaev B, Pharoah PD, Easton DF, Ponder BAJ, Dunning AM; for the SEARCH Team. Hyaluronan-mediated motility receptor gene single nucleotide polymorphisms and risk of breast cancer. Cancer Epidemiology, Biomarkers and Prevention 2008; 17:3618-3620
Mann A, Hogdall E, Ramus SJ, Dicioccio RA, Hogdall C, Quaye L, McGuire V, Whittemore AS, Shah M, Greenberg D, Easton DF, Ponder BAJ, Kjaer SK, Gayther SA, Thompson DJ, Pharoah PD, Song H. Mismatch repair gene polymorphisms and survival in invasive ovarian cancer patients. European Journal of Cancer 2008; 44:2259-65
Meyer KB, Maia A-T, O'Reilly M, Teschendorff AE, Chin S-F, Caldas C, Ponder BAJ. Allele-specific up-regulation of FGFR2 increases susceptibility to breast cancer. PLoS Biology 2008; 6:e108
Pharoah PD, Antoniou AC, Easton DF, Ponder BAJ. Polygenes, risk prediction, and targeted prevention of breast cancer. New England Journal of Medicine 2008; 358:2796-803
Pooley KA, Baynes C, Driver KE, Tyrer J, Azzato EM, Pharoah PD, Easton DF, Ponder BAJ, Dunning AM. Common single-nucleotide polymorphisms in DNA double-strand break repair genes and breast cancer risk. Cancer Epidemiology, Biomarkers and Prevention 2008; 17:3482-9
Quaye L, Gayther SA, Ramus SJ, Di Cioccio RA, McGuire V, Hogdall E, Hogdall C, Blaakr J, Easton DF, Ponder BAJ, Jacobs I, Kjaer SK, Whittemore AS, Pearce CL, Pharoah PD, Song H. The effects of common genetic variants in oncogenes on ovarian cancer survival. Clinical Cancer Research 2008; 14:5833-9
Song H, Koessler T, Ahmed S, Ramus SJ, Kjaer SK, Dicioccio RA, Wozniak E, Hogdall E, Whittemore AS, McGuire V, Ponder BAJ, Turnbull C, Hines S, Rahman N; Breast Cancer Susceptibility Collaboration UK; Eeles RA, Easton DF, Gayther SA, Dunning AM, Pharoah PD. Association study of prostate cancer susceptibility variants with risks of invasive ovarian, breast, and colorectal cancer. Cancer Research 2008; 68:8837-42
Thompson DJ, Healey CS, Baynes C, Kalmyrzaev B, Ahmed S, Dowsett M, Folkerd E, Luben RN, Cox D, Ballinger D, Pharoah PD, Ponder BAJ, Dunning AM, Easton DF; The Studies in Epidemiology and Risks of Cancer Heredity Team. Identification of common variants in the SHBG gene affecting sex hormone-binding globulin levels and breast cancer risk in postmenopausal women. Cancer Epidemiology, Biomarkers and Prevention 2008; 17:3490-8
2007
Baynes C, Healey CS, Pooley KA, Scollen S, Luben RN, Thompson DJ, Pharoah PDP, Easton DF, Ponder BAJ, Dunning AM, SEARCH Breast Canc Study. Common variants in the ATM, BRCA1, BRCA2, CHEK2 and TP53 cancer susceptibility genes are unlikely to increase breast cancer risk. Breast Cancer Res 2007; 9(2):Article R27
Cox A, Dunning AM, Garcia-Closas M, Balasubramanian S, Reed MWR, Pooley KA, Scollen S, Baynes C, Ponder BAJ et al. A common coding variant in CASP8 is associated with breast cancer risk. Nat Genet 2007; 39(3):352-358
Easton DF, Pooley KA, Dunning AM, Pharoah PDP, Thompson D, Ballinger DG, Struewing JP, Morrison J, Field H, Luben R et al. Genome-wide association study identifies novel breast cancer susceptibility loci. Nature 2007; 447(7148):1087-1093
Gayther SA, Song H, Ramus SJ, Kjaer SK, Whittemore AS, Quaye L, Tyrer J, Shadforth D, Hogdall E, Hogdall C, Blaeker J, DiCioccio R et al. Tagging single nucleotide polymorphisms in cell cycle control genes and susceptibility to invasive epithelial ovarian cancer. Cancer Res 2007; 67(7):3027-3035
Pharoah PDP, Tyrer J, Dunning AM, Easton DF, Ponder BAJ, SEARCH Investigators. Association between common variation in 120 candidate genes and breast cancer risk. PLoS Genet 2007; 3(3):401-406
Ramus SJ, Harrington PA, Pye C, DiCioccio RA, Cox MJ, Garlinghouse-Jones K, Oakley-Girvan I, Jacobs IJ, Hardy RM, Whittemore AS, Ponder BAJ, Piver MS, Pharoah PDP, Gayther SA. Contribution of BRCA1 and BRCA2 mutations to inherited ovarian cancer. Hum Mutat 2007; 28(12):1207-1215
Ramus SJ, Harrington PA, Pye C, Peock S, Cook MR, Cox MJ, Jacobs IJ, DiCioccio RA, Whittemore AS, Piver MS, EMBRACE, Easton DF, Ponder BA, Pharoah PD, Gayther SA. Screening for the BRCA1-ins6kbEx13 mutation: potential for misdiagnosis. Mutation in brief #964. Online. Hum Mutat 2007; 28(5):525-526
Ruiz-Llorente S, Montero-Conde C, Milne RL, Moya CM, Cebrian A, Leton R, Cascon A, Mercadillo F, Landa I, Borrego S, de Nanclares GP et al. Association study of 69 genes in the ret pathway identifies low-penetrance loci in sporadic medullary thyroid carcinoma. Cancer Res 2007; 67(19):9561-9567
Samuelson DJ, Hesselson SE, Aperavich BA, Zan YH, Haag JD, Trentham-Dietz A, Hampton JM, Mau B, Chen KS, Baynes C, Khaw KT, Luben R, Perkins B, Shah M, Pharoah PD, Dunning AM, Easton DF, Ponder BA, Gould MN. Rat Mcs5a is a compound quantitative trait locus with orthologous human loci that associate with breast cancer risk. Proc Natl Acad Sci U S A 2007; 104(15):6299-6304
Song H, Ramus SJ, Kjaer SK, Hogdall E, Dicioccio RA, Whittemore AS, McGuire V, Hogdall C, Jacobs IJ, Easton DF, Ponder BA, Dunning AM, Gayther SA, Pharoah PD. Tagging single nucleotide polymorphisms in the BRIP1 gene and susceptibility to breast and ovarian cancer. PLoS ONE 2007; 2(3):e268
Udler M, Maia AT, Cebrian A, Brown C, Greenberg D, Shah M, Caldas C, Dunning A, Easton D, Ponder B, Pharoah P. Common germline genetic variation in antioxidant defense genes and survival after diagnosis of breast cancer. J Clin Oncol 2007; 25(21):3015-3023
2006
Al-Zahrani A, Sandhu MS, Luben RN, Thompson D, Baynes C, Pooley KA, Luccarini C, Munday H, Perkins B, Smith P, Pharoah PDP, Wareham NJ, Easton DF, Ponder BAJ, Dunning AM. IGF1 and IGFBP3 tagging polymorphisms are associated with circulating levels of IGF1, IGFBP3 and risk of breast cancer. Hum Mol Genet 2006; 15(1):1-10
Benusiglio PR, Pharoah PD, Smith PL, Lesueur F, Conroy D, Luben RN, Dew G, Jordan C, Dunning A, Easton DF, Ponder BAJ. HapMap-based study of the 17q21 ERBB2 amplicon in susceptibility to breast cancer. Br J Cancer 2006; 95(12):1689-1695
Carniti C, Belluco S, Riccardi E, Cranston AN, Mondellini P, Ponder BAJ, Scanziani E, Pierotti MA, Bongarzone I. The Ret(C620R) mutation affects renal and enteric development in a mouse model of Hirschsprung's disease. Am J Pathol 2006; 168(4):1262-1275
Cebrian A, Pharoah PD, Ahmed S, Ropero S, Fraga MF, Smith PL, Conroy D, Luben R, Perkins B, Easton DF, Dunning AM, Esteller M, Ponder BAJ. Genetic variants in epigenetic genes and breast cancer risk. Carcinogenesis 2006; 27(8):1661-1669
Cebrian A, Pharoah PD, Ahmed S, Smith PL, Luccarini C, Luben R, Redman K, Munday H, Easton DF, Dunning AM, Ponder BAJ. Tagging single-nucleotide polymorphisms in antioxidant defense enzymes and susceptibility to breast cancer. Cancer Res 2006; 66(2):1225-1233
Cranston A, Carniti C, Martin S, Mondellini P, Hooks Y, Leyland J, Hodgson S, Clarke S, Pierotti M, Ponder BAJ, Bongarzone I. A novel activating mutation in the RET tyrosine kinase domain mediates neoplastic transformation. Mol Endocrinol 2006; 20(7):1633-1643
Cranston AN, Carniti C, Oakhill K, Radzio-Andzelm E, Stone EA, McCallion AS, Hodgson S, Clarke S, Mondellini P, Leyland J, Pierotti MA, Whittaker J, Taylor SS, Bongarzone I, Ponder BAJ. RET is constitutively activated by novel tandem mutations that alter the active site resulting in multiple endocrine neoplasia type 2B. Cancer Res 2006; 66(20):10179-10187
El-Tanani MK, Campbell FC, Crowe P, Erwin P, Harkin DP, Pharoah P, Ponder B, Rudland PS. BRCA1 suppresses osteopontin-mediated breast cancer. J Biol Chem 2006; 281(36):26587-26601
Lesueur F, Cebrian A, Robledo M, Niccoli-Sire P, Svensson KA, Pinson S, Leyland J, Whittaker L, Pharoah PD, Ponder BAJ. Polymorphisms in RET and its coreceptors and ligands as genetic modifiers of multiple endocrine neoplasia type 2A. Cancer Res 2006; 66(2):1177-1180
Lesueur F, Song H, Ahmed S, Luccarini C, Jordan C, Luben R, Easton DF, Dunning AM, Pharoah PD, Ponder BAJ. Single-nucleotide polymorphisms in the RB1 gene and association with breast cancer in the British population. Br J Cancer 2006; 94(12):1921-1926
Oestergaard MZ, Tyrer J, Cebrian A, Shah M, Dunning AM, Ponder BAJ, Easton DF, Pharoah PDP. Interactions between genes involved in the antioxidant defence system and breast cancer risk. Br J Cancer 2006; 95(4):525-531
Pooley KA, Healey CS, Smith PL, Pharoah PDP, Thompson D, Tee L, West J, Jordan C, Easton DF, Ponder BAJ, Dunning AM. Association of the progesterone receptor gene with breast cancer risk: A single-nucleotide polymorphism tagging approach. Cancer Epidemiol Biomarkers Prev 2006; 15(4):675-682
Song HL, Ramus SJ, Quaye L, DiCioccio RA, Tyrer J, Lomas E, Shadforth D, Hogdall E, Hogdall C, McGuire V, Whittemore AS, Easton DF, Ponder BAJ, Kjaer SK, Pharoah PDP, Gayther SA. Common variants in mismatch repair genes and risk of invasive ovarian cancer. Carcinogenesis 2006; 27(11):2235-2242
Song HL, Ramus SJ, Shadforth D, Quaye L, Kjaer SK, DiCioccio RA, Dunning AM, Hogdall E, Hogdall C, Whittemore AS, McGuire V, Lesueur F, Easton DF, Jacobs IJ, Ponder BAJ, Gayther SA, Pharoah PDP. Common variants in RB1 gene and risk of invasive ovarian cancer. Cancer Res 2006; 66(20):10220-10226
Sternlicht MD, Dunning AM, Moore DH, Pharoah PDP, Ginzinger DG, Chin K, Gray JW, Waldman FM, Ponder BAJ, Werb Z. Prognostic value of PAI1 in invasive breast cancer: Evidence that tumor-specific factors are more important than genetic variation in regulating PAI1 expression. Cancer Epidemiol Biomarkers Prev 2006; 15(11):2107-2114
Walker L, Thompson D, Easton D, Ponder B, Ponder M, Frayling I, Baralle D. A prospective study of neurofibromatosis type 1 cancer incidence in the UK. Br J Cancer 2006; 95(2):233-238
Warren R, Skinner J, Sala E, Denton E, Dowsett M, Folkerd E, Healey CS, Dunning A, Doody D, Ponder B, Luben RN, Day NE, Easton D. Associations among mammographic density, circulating sex hormones, and polymorphisms in sex hormone metabolism genes in postmenopausal women. Cancer Epidemiol Biomarkers Prev 2006; 15(8):1502-1508
2005
Auranen A, Song HL, Waterfall C, DiCioccio RA, Kuschel B, Kjaer SK, Hogdall E, Hogdall C, Stratton J, Whittemore AS, Easton DF, Ponder BAJ, Novik KL, Dunning AM, Gayther S, Pharoah PDP. Polymorphisms in DNA repair genes and epithelial ovarian cancer risk. Int J Cancer 2005; 117(4):611-618
Benusiglio PR, Lesueur F, Luccarini C, Conroy DM, Shah M, Easton DF, Day NE, Dunning AM, Pharoah PD, Ponder BAJ. Common ERBB2 polymorphisms and risk of breast cancer in a white British population: a case-control study. Breast Cancer Res 2005; 7(2):R204-R209
Benusiglio PR, Lesueur F, Luccarini C, McIntosh J, Luben RN, Smith P, Dunning A, Easton DF, Ponder BAJ, Pharoah PD. Common variation in EMSY and risk of breast and ovarian cancer: a case-control study using HapMap tagging SNPs. BMC Cancer 2005; 5:Article 81
Benusiglio PR, Luccarini C, Ajai O, Ponder BAJ, Pharoah PD. Reply: a bias in genotyping of the ERBB2 (HER2) Ile655Val variant. Carcinogenesis 2005; 26(12):2213-2213
Bockmann M, Hilken G, Schmidt A, Cranston AN, Tannapfel A, Drosten M, Frilling A, Ponder BAJ, Putzer BM. Novel SRESPHP peptide mediates specific binding to primary medullary thyroid carcinoma after systemic injection. Hum Gene Ther 2005; 16(11):1267-1275
Cascon A, Cebrian A, Pollan M, Ruiz-Llorente S, Montero-Conde C, Leton R, Gutierrez R, Lesueur F, Milne RL, Gonzalez-Albarran O, Lucas-Morante T, Benitez J, Ponder BAJ, Robledo M. Succinate dehydrogenase D variants do not constitute a risk factor for developing C cell hyperplasia or sporadic medullary thyroid carcinoma. J Clin Endocrinol Metab 2005; 90(4):2127-2130
Cebrian A, Lesueur F, Martin S, Leyland J, Ahmed S, Luccarini C, Smith PL, Luben R, Whittaker J, Pharoah PD, Dunning AM, Ponder BAJ. Polymorphisms in the initiators of RET (rearranged during transfection) signaling pathway and susceptibility to sporadic medullary thyroid carcinoma. J Clin Endocrinol Metab 2005; 90(11):6268-6274
Dunning AM, Dowsett M, Healey CS, Luben RN, Folkerd E, Pharoah PDP, Easton DF, Day NE, Ponder BAJ. Re: Polymorphisms associated with circulating sex hormone levels in postmenopausal women - Response. J Natl Cancer Inst 2005; 97(2):153-154
Hu SP, Day NE, Li DR, Luben RN, Cai KL, Ou-Yang T, Li B, Lu XZ, Ponder BAJ. Further evidence for an HLA-related recessive mutation in nasopharyngeal carcinoma among the Chinese. Br J Cancer 2005; 92(5):967-970
Kuschel B, Chenevix-Trench G, Spurdle AB, Chen XQ, Hopper JL, Giles GG, McCredie M, Chang-Claude J, Gregory CS, Day NE, Easton DF, Ponder BAJ, Dunning AM, Pharoah PDP. Common polymorphisms in ERCC2 (Xeroderma pigmentosum D) are not associated with breast cancer risk. Cancer Epidemiol Biomarkers Prev 2005; 14(7):1828-1831
Lesueur F, Cebrian A, Cranston A, Leyland J, Faid TM, Clements MR, Robledo M, Whittaker J, Ponder BAJ. Germline homozygous mutations at codon 804 in the RET protooncogene in medullary thyroid carcinoma/multiple endocrine neoplasia type 2A patients. J Clin Endocrinol Metab 2005; 90(6):3454-3457
Lesueur F, Pharoah PD, Laing S, Ahmed S, Jordan C, Smith PL, Luben R, Wareham NJ, Easton DF, Dunning AM, Ponder BAJ. Allelic association of the human homologue of the mouse modifier Ptprj with breast cancer. Hum Mol Genet 2005; 14(16):2349-2356
2004
Cranston A, Howard L, Howard CV. Quantitative phenotyping as an efficient means to estimate C-cell number in a knock-in mouse model of MEN2B. Transgenic Res 2004; 13(4):339-348
Daigo Y, Takayama D, Ponder BA, Caldas C, Ward SM, Sanders KM, Fujino MA. Novel human, mouse and xenopus genes encoding a member of the RAS superfamily of low-molecular-weight GTP-binding proteins and its downregulation in W/W-v mouse jejunum. J Gastroenterol Hepatol 2004; 19(2):211-217
DiCioccio RA, Song HL, Waterfall C, Kimura MT, Nagase H, McGuire V, Hogdall E, Shah MN, Luben RN, Easton DF, Jacobs IJ, Ponder BAJ, Whittemore AS, Gayther SA, Pharoah PDP, Kruger-Kjaer S. STK15 polymorphisms and association with risk of invasive ovarian cancer. Cancer Epidemiol Biomarkers Prev 2004; 13(10):1589-1594
Drosten M, Hilken G, Bockmann M, Rodicker F, Mise N, Cranston AN, Dahmen U, Ponder BAJ, Putzer BM. Role of MEN2A-derived RET in maintenance and proliferation of medullary thyroid carcinoma. J Natl Cancer Inst 2004; 96(16):1231-1239
Dunning AM, Dowsett M, Healey CS, Tee L, Luben RN, Folkerd E, Novik KL, Kelemen L, Ogata S, Pharoah PDP, Easton DF, Day NE, Ponder BAJ. Polymorphisms associated with circulating sex hormone levels in postmenopausal women. J Natl Cancer Inst 2004; 96(12):936-945
Easton D, McGuffog L, Thompson D, Dunning A, Tee L, Baynes C, Healey C, Pharoah P, Ponder B, Seal S, Barfoot R, Sodha N et al. CHEK2*1100delC and susceptibility to breast cancer: A collaborative analysis involving 10,860 breast cancer cases and 9,065 controls from 10 studies. Am J Hum Genet 2004; 74(6):1175-1182
Lakhani SR, Manek S, Penault-Llorca F, Flanagan A, Arnout L, Merrett S, McGuffog L, Steele D, Devilee P, Klijn JGM, Meijers-Heijboer H, Radice P, Pilotti S, Nevanlinna H, Butzow R, Sobol H, Jacquemier J, Lyonet DS, Neuhausen SL, Weber B, Wagner T, Winqvist R, Bignon YJ, Monti F, Schmitt F, Lenoir G, Seitz S, Hamman U, Pharoah P, Lane G, Ponder B, Bishop DT, Easton DF. Pathology of ovarian cancers in BRCA1 and BRCA2 carriers. Clin Cancer Res 2004; 10(7):2473-2481
MacPherson G, Healey CS, Teare MD, Balasubramanian SP, Reed MWR, Pharoah PDP, Ponder BAJ, Meath M, Bhattacharyya NP, Cox A. Association of a common variant of the CASP8 gene with reduced risk of breast cancer. J Natl Cancer Inst 2004; 96(24):1866-1869
Werness BA, Ramus SJ, DiCioccio RA, Whittemore AS, Garlinghouse-Jones K, Oakley-Girvan I, Tsukada Y, Harrington P, Gayther SA, Ponder BAJ, Piver MS. Histopathology, FIGO stage, and BRCA mutation status of ovarian cancers from the Gilda Radner Familial Ovarian Cancer Registry. Int J Gynecol Pathol 2004; 23(1):29-34
Whittemore AS, Balise RR, Pharoah PDP, DiCioccio RA, Oakley-Girvan I, Ramus SJ, Daly M, Usinowicz MB, Garlinghouse-Jones K, Ponder BAJ, Buys S, Senie R, Andrulis I, John E, Hopper JL, Piver MS, kConFab. Oral contraceptive use and ovarian cancer risk among carriers of BRCA1 or BRCA2 mutations. Br J Cancer 2004; 91(11):1911-1915
2003
Auranen A, Spurdle AB, Chen XQ, Lipscombe J, Purdie DM, Hopper JL, Green A, Healey CS, Redman K, Dunning AM, Pharoah PD, Easton DF, Ponder BAJ, Chenevix-Trench G, Novik KL. BRCA2 Arg372His polymorphism and epithelial ovarian cancer risk. Int J Cancer 2003; 103(3):427-430
Cranston AN, Ponder BAJ. Modulation of medullary thyroid carcinoma penetrance suggests the presence of modifier genes in a RET transgenic mouse model. Cancer Res 2003; 63(16):4777-4780
Daigo Y, Takayama I, Ponder BAJ, Caldas C, Ward SM, Sanders KM, Fujino MA. Differential gene expression in the murine gastric fundus lacking interstitial cells of Cajal. BMC Gastroenterol 2003; 3:Article 14
Daigo Y, Takayama I, Ponder BAJ, Caldas C, Ward SM, Sanders KM, Fujino MA. Differential gene expression profile in the small intestines of mice lacking pacemaker interstitial cells of Cajal. BMC Gastroenterol 2003; 3:Article 17
Dunning AM, Ellis PD, McBride S, Kirschenlohr HL, Healey CS, Kemp PR, Luben RN, Chang-Claude J, Mannermaa A, Kataja V, Pharoah PDP, Easton DF, Ponder BAJ, Metcalfe JC. A transforming growth factor beta 1 signal peptide variant increases secretion in vitro and is associated with increased incidence of invasive breast cancer. Cancer Res 2003; 63(10):2610-2615
Edwards SM, Kote-Jarai Z, Meitz J, Hamoudi R, Hope Q, Osin P, Jackson R, Southgate C, Singh R, Falconer A, Dearnaley DP, Ardern-Jones A, Murkin A, Dowe A, Kelly J, Williams S, Oram R, Stevens M, Teare DM, Ponder BAJ, Gayther SA, Easton DF, Eeles RA, Canc Res UK British Prostate Grp U, British Assoc Urological Surg Sect. Two percent of men with early-onset prostate cancer harbor germline mutations in the BRCA2 gene. Am J Hum Genet 2003; 72(1):1-12
Ewart-Toland A, Briassouli P, de Koning JP, Mao JH, Yuan JW, Chan F, MacCarthy-Morrogh L, Ponder BAJ, Nagase H, Burn J, Ball S, Almeida M, Linardopoulos S, Balmain A. Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human. Nat Genet 2003; 34(4):403-412
Hughes-Davies L, Huntsman D, Ruas M, Fuks F, Bye J, Chin SF, Milner J, Brown LA, Hsu F, Gilks B, Nielsen T, Schulzer M, Chia S, Ragaz J, Cahn A, Linger L, Ozdag H, Cattaneo E, Jordanova ES, Schuuring E, Yu DS, Venkitaraman A, Ponder B, Doherty A, Aparicio S, Bentley D, Theillet C, Ponting CP, Caldas C, Kouzarides T. EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer. Cell 2003; 115(5):523-535
Kuschel B, Auranen A, Gregory CS, Day NE, Easton DF, Ponder BAJ, Dunning AM, Pharoah PDP. Common polymorphisms in Checkpoint kinase 2 are not associated with breast cancer risk. Cancer Epidemiol Biomarkers Prev 2003; 12(8):809-812
Ramus SJ, Pharoah PDP, Harrington P, Pye C, Werness B, Bobrow L, Ayhan A, Wells D, Fishman A, Gore M, DiCioccio RA, Piver MS, Whittemore AS, Ponder BAJ, Gayther SA. BRCA1/2 mutation status influences somatic genetic progression in inherited and sporadic epithelial ovarian cancer cases. Cancer Res 2003; 63(2):417-423
Weinhausel A, Behmel A, Ponder BAJ, Haas OA, Niederle B, Gessl A, Vierhapper H, Pfragner R. Long-term follow up of a "sporadic" unilateral pheochromocytoma revealing multiple endocrine neoplasia MEN2A-2 in an elderly woman. Endocr Pathol 2003; 14(4):375-382
2002
Antoniou AC, Pharoah PDP, McMullan G, Day NE, Stratton MR, Peto J, Ponder BJ, Easton DF. A comprehensive model for familial breast cancer incorporating BRCA1, BRCA2 and other genes. Br J Cancer 2002; 86(1):76-83
Goode EL, Dunning AM, Kuschel B, Healey CS, Day NE, Ponder BAJ, Easton DF, Pharoah PDP. Effect of germ-line genetic variation on breast cancer survival in a population-based study. Cancer Res 2002; 62(11):3052-3057
Kuschel B, Auranen A, McBride S, Novik KL, Antoniou A, Lipscombe JM, Day NE, Easton DF, Ponder BAJ, Pharoah PDP, Dunning A. Variants in DNA double-strand break repair genes and breast cancer susceptibility. Hum Mol Genet 2002; 11(12):1399-1407
Ozdag H, Batley SJ, Forsti A, Iyer NG, Daigo Y, Boutell J, Arends MJ, Ponder BAJ, Kouzarides T, Caldas C. Mutation analysis of CBP and PCAF reveals rare inactivating mutations in cancer cell lines but not In primary tumours. Br J Cancer 2002; 87(10):1162-1165
Pharoah PDP, Antoniou A, Bobrow M, Zimmern RL, Easton DF, Ponder BAJ. Polygenic susceptibility to breast cancer and implications for prevention. Nat Genet 2002; 31(1):33-36
Thompson D, Szabo CI, Mangion J, Oldenburg RA, Odefrey F, Seal S, Barfoot R, Kroeze-Jansema K, Teare D, Rahman N et al. Evaluation of linkage of breast cancer to the putative BRCA3 locus on chromosome 13q21 in 128 multiple case families from the Breast Cancer Linkage Consortium. Proc Natl Acad Sci U S A 2002; 99(2):827-831
Other Publications
Mulvany F, Ponder BA. Breast Cancer Research - the first ten years. Breast Cancer Research 2008; 10:103
Pharoah PDP, Dunning AM, Ponder BAJ, Easton DF. The reliable identification of disease-gene associations. Cancer Epidemiol Biomarkers Prev 2005; 14(6):1362-1362
Ponder BA, Antoniou A, Dunning A, Easton DF, Pharoah PD. Polygenic inherited predisposition to breast cancer. Cold Spring Harbor Symp Quant Biol 2005; 70:35-41
Pharoah PDP, Dunning AM, Ponder BAJ, Easton DF. Association studies for finding cancer-susceptibility genetic variants. Nat Rev Cancer 2004; 4(11):850-860
Balmain A, Gray J, Ponder B. The genetics and genomics of cancer. Nat Genet 2003; 33(Supp):238-244
Jordan VC, Ponder BAJ. Introducing a new section to Breast Cancer Research: Endocrinology and hormone therapy. Breast Cancer Res 2003; 5(6):281-283
Basham VM, Lipscombe JM, Ward JM, Gayther SA, Ponder BAJ, Easton DF, Pharoah PDP. BRCA1 and BRCA2 mutations in a population-based study of male breast cancer. Breast Cancer Res 2002; 4(1):R2-U9
Pharoah PDP, Ponder BAJ. The genetics of ovarian cancer. Best Pract Res Clin Obstet Gynaecol 2002; 16(4):449-+
