Selected Publications

McWhir, J., Selfridge, J., Harrison, D.J., Squires, S. and Melton, D.W. 1993. Transgenic models with DNA repair gene (ERCC1) deficiency have elevated levels of p53 and liver nuclear abnormalities. Nature Genetics 5: 217-224.

Bentley, D.J., Selfridge, J., Millar, J.K., Samuel, K., Hole, N., Ansell, J.D. and Melton, D.W. 1996. DNA ligase I is required for foetal liver erythropoiesis but is not essential for mammalian cell viability. Nature Genetics 13: 489-491.

Nunez, F., Chipchase, M.D., Clarke, A.R. and Melton, D.W. 2000. Nucleotide excision repair gene (ERCC1) deficiency causes G2 arrest in hepatocytes and a reduction in liver binucleation: the role of p53 and p21. FASEB J. 14:1073-1082.

Tomescu, D., Kavanagh, G., Ha, T., Campbell, H. and Melton, D.W. 2001. Nucleotide excision repair gene XPD polymorphisms and genetic predisposition to melanoma. Carcinogenesis 22: 403-408.

Selfridge, J., Hsia, K.-T. and Melton, D.W. 2001. Correction of liver dysfunction in DNA repair-deficient transgenic models with an ERCC1 transgene. Nucleic Acids Research 29: 4541-4550.