Selected Publications

Strathdee, G., Appleton, K., Illand, M., Millan, D.W.M., Sargent, J., Paul, J and Brown, R. (2001) Primary ovarian carcinomas display multiple methylator phenotypes involving known tumor suppressor genes. Am. J. Pathol. 158, 1121-1127.

Plumb, J.A., Strathdee, G., Sludden, J., Kaye, S.B. and R. Brown (2000) Reversal of drug resistance in human tumor xenografts by 2’-deoxy-5-azacytidine-induced demethylation of the hMLH1 gene promoter. Cancer Res. 60, 6039-6044

Mackay, H.J., Cameron, D., Rahilly, M., Mackean, M.J., Paul, J., Kaye, S.B. and Brown, R. (2000) Reduced MLH1 expression in breast tumours after primary chemotherapy predicts disease-free survival. J. Clin. Oncol. 18, 87-93.

Moreland, N.J., Illand, M. Kim, Y.T., Paul, J. and Brown, R. (1999) Modulation of drug resistance mediated by loss of mismatch repair by the DNA polymerase inhibitor aphidicolin. Cancer Res. 59, 2102-2106.

Durant, S.T., Morris, M.M., Illand, M., McKay, H.J., McCormick,C., Hirst, G.L., Borts, R.H. and R. Brown (1999). Dependence on RAD52 and RAD1 for anticancer drug resistance mediated by inactivation of mismatch repair genes. Current Biology, 9, 51-54.