Selected Publications
Pritchard, C.A., Samuels, M.L., Bosch, E. &
McMahon, M. (1995) Conditional oncogenic forms of the A-Raf and B-Raf
protein kinases display different biological and biochemical properties
in NIH 3T3 cells. Mol. Cell. Biol. 15, 6430-6442.
Pritchard, C., Bolin, L., Slattery, R., Murray, R. & McMahon, M.
(1996) Post-natal lethality, neurological and gastrointestinal defects
accompany the targeted disruption of the A-Raf protein kinase in the mouse.
Current Biology. 6, 614-617.
Luckett, J., Huser, M., Giagtzoglou, N., Brown, J. & Pritchard,
C.A. Expression of the A-raf proto-oncogene in the normal adult and
embryonic mouse. (2000). Cell Growth and Differentiation. 11. 163-171.
Hüser, M., Luckett, J., Chiloeches, A., Mercer, K., Iwobi, M., Giblett,
S., Sun X-M., Brown, J., Marais, R. & Pritchard, C. (2001) MEK
kinase activity is not necessary for Raf-1 function. EMBO J. 20:
1940-1951.
Mercer, K., Chiloeches, A., Hüser, M., Kiernan, M., Marais, R. and
Pritchard, C. (2001) ERK signalling and transformation by Ras and
Src oncogenes are not impaired in cells lacking A-Raf. Oncogene.
In press.