Selected Publications

Itoh Y, Kajita M, Kinoh H, Mori H, Okada A, Seiki M : Membrane-type 4 matrix metalloproteinase (MT4-MMP, MMP-17) is a glycosyl-phosphatidyl inositol (GPI)-anchored proteinase. J. Biol. Chem., 274, 34260-34266, 1999

Kojima S, Itoh Y, Matsumoto S, Masuho Y, and Seiki M: Membrane-type 6 matrix metalloproteinase (MT6-MMP, MMP-25) is the second glycosyl-phosphatidyl inositol (GPI)-anchored MMP. FEBS Letters, 480, 142-146, 2000

Kajita M, Itoh Y, Chiba T, Mori H, Okada A, Kinoh H, and Seiki M: Membrane-Type 1 Matrix Metalloproteinase Cleaves CD44 And Promotes Cell Migration. J. Cell Biol., 153, 893-904, 2001

Itoh Y, Takamura A, Ito N, Maru Y, Sato H, Suenaga N, Aoki T and Seiki M: Homophilic complex formation of MT1-MMP facilitates proMMP-2 activation on the cell surface and promotes tumor cell invasion. EMBO J., 20, 4782-4793, 2001

Uekita T, Itoh Y, Yana I, Ohno H, and Seiki M: Cytoplasmic tail dependent internalization of membrane-type 1 matrix metalloproteinase (MT1-MMP) is important for its invasion-promoting activity. J. Cell Biol., 155, 1345–1356, 2001