Selected Publications

Donald A, McHardy T, Rowlands MG, Hunter LK, Davies TG, Berdini V, Boyle RG, Aherne GW, Garrett MD, Collins I. Rapid evolution of 6-phenylpurine inhibitors of protein kinase B through structure-based design. J Med Chem 2007; 50: 2289-2292.

Collins I, Caldwell J, Fonseca T, Donald A, Bavetsias V, Rowlands MG, Hunter LK, Garrett MD, Davies TG, Berdini V, Woodhead S, Davis D, Seavers LCA, Wyatt PG, McDonald E. Structure-based design of isoquinoline-5-sulfonamide inhibitors of protein kinase B. Bioorg Med Chem 2006; 14: 1255-1273.

Collins I, Molife R, Kaye SB, Workman P. Rational drug design of small molecule anticancer agents: Preclinical discovery. The Cancer Handbook 2nd Edition (Alison MR, Ed), John Wiley & Sons Ltd, Chichester, UK 2007, pp1199-1215.

Caldwell JJ, Cheung KM, Collins I. Synthesis of 4-(cyclic dialkylamino)-&-azaindoles by microwave heating of 4-halo-7-azaindoles and cyclic secondary amines. Tetrahedron Lett 2007; 48: 1527-129.

Caldwell JJ, Collins I. Rapid synthesis of 4-benzyl-4-aminopiperidines by addition of Grignard reagents to N-(1-BOC-piperidin-4-ylidene)-tert-butanesulfinyl imine. Synlett 2006; 16: 2565-2568.