Selected Publications

Luangdilok S, Box C, Patterson L, Court W, Harrington H, Pitkin L, Rhŷs-Evans P, O-charoenrat P, Eccles S. Syk tyrosine kinase is linked to cell motility and progression in squamous cell carcinomas of the head and neck. Cancer Res 2007; 67(16): 7907-7916.

Peak J, Jones NP, Hobbs S, Katan M, Eccles SA. Phospholipase Cγ1 regulates the Rap GEF1-Rap1 signalling axis in the control of tumour cell adhesion. Oncogene 2008; 27(20): 2823-2832.

Eccles SA, Massey M, Raynaud F et al. NVP-AUY922: a novel synthetic resorcinylic isoxazole amide HSP90 inhibitor with potent activity against xenograft tumor growth, angiogenesis and metastasis. Cancer Res 2008; In press.

Raynaud FI, Eccles S, Clarke PA, et al. Pharmacological characterisation of a potent inhibitor of class 1 phosphatidylinositide 3-kinases. Cancer Res 2007; 67(12): 5840-5850.

Eccles SA, Welch D. Metastasis: recent discoveries and novel therapeutic strategies. Lancet 2007; 369(9574): 1742-1757.