Selected Publications

Ceschini S, Keeley A, McAlister MSB, Oram M, Phelan J, Pearl LH, Tsaneva IR, Barrett TE (2001) Crystal structure of the fission yeast mitochondrial Holliday junction resolvase Ydc2, EMBO J., 20 6601-6611.

Dajani R, Fraser E, Roe SM, Young N, Good V, Dale TC and Pearl LH (2001) Crystal structure of glycogen synthase kinase 3b: Structural basis for phosphate-primed substrate specificity and auto-inhibition, Cell 105, 721-723.

Prodromou C, Panaretou B, Chohan S, Siligardi G, O'Brien R, Ladbury JE, Roe SM, Piper PW and Pearl LH (2000) The ATPase cycle of Hsp90 drives a molecular 'clamp' via transient dimerisation of the N-terminal domains, EMBO J., 19, 4383-4392.

Barrett TE, Schärer OD, Savva R, Brown T, Jiricny J, Verdine GL and Pearl LH (1999) Crystal structure of a thwarted mismatch glycosylase DNA repair complex, EMBO J., 18, 6599-6609.

Barrett TE, Savva R, Panayotou G, Barlow T, Brown TA, Jiricnyv J and Pearl LH (1998) Crystal structure of a G:T/U mismatch DNA glycosylase: Mismatch recognition by Complementary-Strand interactions, Cell, 92, 117-129.