Selected Publications

Bullock SL and Ish-Horowicz D. Conserved signals and machinery for RNA transport in Drosophila oogenesis and embryogenesis. Nature 2001; 414: 611-616. PubMed

Morales AV, Yasuda Y and Ish-Horowicz D. Periodic Lunatic fringe expression during segmentation is controlled by a cyclic transcriptional enhancer responsive to Notch signaling. Dev Cell 2002; 3: 63-74. PubMed

Bullock S, Zicha D and Ish-Horowicz D. The Drosophila hairy RNA localization signal modulates the kinetics of cytoplasmic mRNA transport. EMBO J 2003; 10: 2484-2494. PubMed PDF (UKPMC)

Hughes JR, Bullock SL and Ish-Horowicz D. inscuteable mRNA localization is dynein-dependent and regulates apicobasal polarity and spindle length in Drosophila neuroblasts. Curr Biol 2004; 14: 1950-1956. PubMed

Jennings BH, Pickles LM, Wainwright SM, Roe SM, Pearl LH and Ish-Horowicz D. Molecular recognition of transcriptional repressor motifs by the WD domain of the Groucho/TLE corepressor. Mol Cell 2006; 22: 645-655. PubMed

Primary Research Publications

2008

Jennings BH, Ish-Horowicz D. The Groucho/TLE/Grg family of transcriptional co-repressors. Genome Biol 2008;9(1):205

Jennings BH, Wainwright SM, Ish-Horowicz D. Differential in vivo requirements for oligomerization during Groucho mediated repression. EMBO Rep 2008;9(1):76-83

2006

Jennings BH, Pickles LM, Wainwright SM, Roe SM, Pearl LH, Ish-Horowicz D. Molecular recognition of transcriptional repressor motifs by the WD domain of the Groucho/TLE corepressor. Mol Cell 2006; 22(5):645-655

Kim S-H, Rowe J, Fujii H, Jones R, Schmierer B, Kong BW, Kuchler K, Foster D, Ish-Horowicz D, Peters G. Upregulation of chicken p15(INK4b) at senescence and in the developing brain. J Cell Sci 2006; 119(12):2435-2443

2005

Kidd T, Abu-Shumays R, Katzen A, Sisson JC, Jimenez G, Pinchin S, Sullivan W, Ish-Horowicz D. The epsilon-subunit of mitochondrial ATP synthase is required for normal spindle orientation during the Drosophila embryonic divisions. Genetics 2005; 170(2):697-708

2004

Aerne B, Ish-Horowicz D. Receptor tyrosine phosphatase psi is required for Delta/Notch signalling and cyclic gene expression in the presomitic mesoderm. receptor tyrosine phosphatase is required for Delta/Notch signalling and cyclic gene expression in the presomitic mesoderm. Development 2004; 131(14):3391-3399

Bullock SL, Stauber M, Prell A, Hughes JR, Ish-Horowicz D, Schmidt-Ott U. Differential cytoplasmic mRNA localisation adjusts pair-rule transcription factor activity to cytoarchitecture in dipteran evolution. Development 2004; 131(17):4251-4261

Hozumi K, Negishi N, Suzuki D, Abe N, Sotomaru Y, Tamaoki N, Mailhos C, Ish-Horowicz D, Habu S, Owen MJ. Delta-like 1 is necessary for the generation of marginal zone B cells but not T cells in vivo. Nat Immunol 2004; 5(6):638-644

Hughes JR, Bullock SL, Ish-Horowicz D. inscuteable mRNA localization is dynein-dependent and regulates apicobasal polarity and spindle length in Drosophila neuroblasts. Curr Biol 2004; 14(21):1950-1956

Jennings BH, Shah S, Yamaguchi Y, Seki M, Phillips RG, Handa H, Ish-Horowicz D. Locus-specific requirements for Spt5 in transcriptional activation and repression in Drosophila. Curr Biol 2004; 14(18):1680-1684

2003

Aerne B, Stoker A, Ish-Horowicz D. Chick receptor tyrosine phosphatase Psi is dynamically expressed during somitogenesis. Gene Expr Patterns 2003; 3(3):325-329

Bullock SL, Zicha D, Ish-Horowicz D. The Drosophila hairy RNA localization signal modulates the kinetics of cytoplasmic mRNA transport. EMBO J 2003; 22(10):2484-2494

Kim S-H, Mitchell M, Fujii H, Llanos S, Peters G. Absence of p16(INK4a) and truncation of ARF tumor suppressors in chickens. Proc Natl Acad Sci U S A 2003; 100(1):211-216

Le Roux I, Lewis J, Ish-Horowicz D. Notch activity is required to maintain floorplate identity and to control neurogenesis in the chick hindbrain and spinal cord. Int J Dev Biol 2003; 47(4):263-272

Maclaren A, Clark W, Black EJ, Gregory D, Fujii H, Gillespie DAF. v-Jun stimulates both cdk2 kinase activity and G1/S progression via transcriptional repression of p2l CIP1. Oncogene 2003; 22(16):2383-2395

McLaughlin D, Karlsson F, Tian N, Pratt T, Bullock SL, Wilson VA, Price DJ, Mason JO. Specific modification of heparan sulphate is required for normal cerebral cortical development. Mech Dev 2003; 120(12):1481-1488

2002

Morales AV, Yasuda Y, Ish-Horowicz D. Periodic Lunatic fringe expression is controlled during segmentation by a cyclic transcriptional enhancer responsive to Notch signaling. Dev Cell 2002; 3(1):63-74

Other Publications

Jennings BH, Ish-Horowicz D. The Groucho/TLE/Grg family of transcriptional co-repressors. Genome Biol 2008; 9(1):Article 205

Bullock SL, Ish-Horowicz D. Cell polarity: Oskar seeks PARtner for a stable relationship. Nat Cell Biol 2002; 4(5):E117-E118

Jennings B. Stopping transcription in its tracks. Nat Genet 2002; 32(1):87-88