Selected Publications

Mäkinen T, Adams RA, Bailey J, Lu Q, Ziemiecki A, Alitalo K, Klein R and Wilkinson GA. PDZ interaction site in ephrinB2 is required for the remodeling of lymphatic vasculature. Genes Dev 2005; 19: 397-410. PubMed Full text

Petrova TV, Mäkinen T, Mäkelä TP, Saarela J, Virtanen I, Ferrell RE, Finegold DG, Kerjaschki D, Ylä-Herttuala S and Alitalo K. Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor. EMBO J 2002; 21: 4593-4599. PubMed PDF (UKPMC)

Mäkinen T, Veikkola T, Mustjoki S, Karpanen T, Catimel B, Nice EC, Wise L, Mercer A, Kowalski H, Kerjaschki D, Stacker SA, Achen MG and Alitalo K. Isolated lymphatic endothelial cells transduce growth, survival and migration signals via the VEGF-C/D receptor VEGFR-3. EMBO J 2001; 20: 4762-4773. PubMed PDF (UKPMC)

Mäkinen T, Jussila L, Veikkola T, Karpanen T, Kettunen MI, Pulkkanen KJ, Kauppinen R, Jackson DG, Kubo H, Nishikawa S-I, Ylä-Herttuala S and Alitalo K. Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3. Nature Med 2001; 2: 199-205. PubMed

Primary Research Publications

2009

Bazigou E, Xie S, Chen C, Weston A, Miura N, Sorokin L, Adams R, Muro AF, Sheppard D, Makinen T Integrin-alpha9 is required for fibronectin matrix assembly during lymphatic valve morphogenesis. Dev Cell 2009 Aug;17(2):175-86

2008

Haiko P, Makinen T, Keskitalo S, Taipale J, Karkkainen MJ, Baldwin ME, Stacker SA,Achen MG. and Alitalo K. Deletion of vascular endothelial growth factor C (VEGF-C) and VEGFD is not equivalent to VEGF receptor 3 deletion in mouse embryos. Mol. Cell Biol 2008;28(15):4843-50

2007

Hosking B, Mäkinen T. Lymphatic vasculature: A molecular perspective. Bioessays 2007; 29(12):1192-1202

Other Publications

Mäkinen T, Norrmen C, Petrova TV. Molecular mechanisms of lymphatic vascular development. Cellular and Molecular Life Sciences 2007; 64: 1915-29.