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London Research Institute
 
Svend Petersen-Mahrt
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Publications

Selected Publications

Coker HA, Morgan HD and Petersen-Mahrt SK. Genetic and in vitro assays of DNA deamination. In: Campbell JL, Modrich P (ed.), Methods in Enzymology, Vol 408: DNA Repair. London: Academic Press, 2006; 156-170. PubMed

Petersen-Mahrt S. DNA deamination in immunity. Immunol Rev 2005; 203: 80-97. PubMed

Morgan HD, Dean W, Coker HA, Reik W and Petersen-Mahrt SK. Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming. J Biol Chem 2004; 279: 52353-52360. PubMed

Petersen-Mahrt SK and Neuberger MS. In vitro deamination of cytosine to uracil in single-stranded DNA by apolipoprotein B editing complex catalytic subunit 1 (APOBEC1). J Biol Chem 2003; 278: 19583-19586. PubMed

Petersen-Mahrt SK, Harris RS and Neuberger MS. AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification. Nature 2002; 418: 99-103. PubMed


Primary Research Publications

2009

Pauklin S, Burkert JS, Martin J, Osman F, Weller S, Boulton S, Whitby MC, Petersen-Mahrt SK. Alternative Induction of Meiotic Recombination from Single Base Lesions of DNA Deaminases. Genetics. 2009 Feb 24

Pauklin S, Sern ndez IV, Bachmann G, Ramiro AR, Petersen-Mahrt SK. Estrogen directly activates AID transcription and function. J Exp Med. 2009 Jan 16;206(1):99-111.

Pauklin S, Petersen-Mahrt SK. Progesterone inhibits activation-induced deaminase by binding to the promoter. J Immunol 2009 Jul 15;183(2):1238-44

2007

Akusjarvi G, Kreivi J-P, Petersen-Mahrt S. Messenger RNA in Eukaryotes. Encyclopedia of Life Sciences, e-Published 21 Dec 2007, doi: 10.1002/9780470015902.a0000875.pub2.

Coker HA, Petersen-Mahrt SK. The nuclear DNA deaminase AID functions distributively whereas cytoplasmic APOBEC3G has a processive mode of action. DNA Repair 2007; 6(2):235-243

2005

Conticello SG, Thomas CJF, Petersen-Mahrt SK, Neuberger MS. Evolution of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases. Mol Biol Evol 2005; 22(2):367-377

2004

Beale RCL, Petersen-Mahrt SK, Watt IN, Harris RS, Rada C, Neuberger MS. Comparison of the differential context-dependence of DNA deamination by APOBEC enzymes: correlation with mutation spectra in vivo. J Mol Biol 2004; 337(3):585-596

Morgan HD, Dean W, Coker HA, Reik W, Petersen-Mahrt SK. Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues - Implications for epigenetic reprogramming. J Biol Chem 2004; 279(50):52353-52360


Other Publications

Petersen-Mahrt SK, Coker HA, Pauklin S. DNA deaminases: AIDing hormones in immunity and cancer. J Mol Med 2009 Sep;87(9):893-7.

Coker HA, Petersen-Mahrt SK. AID's distributive mode of action: A definition. DNA Repair 2007; 6(6):693-694

Coker HA, Morgan HD, Petersen-Mahrt SK. Genetic and in vitro assays of DNA deamination. Methods Enzymol 2006; 408:156-170

Petersen-Mahrt S. DNA deamination in immunity. Immunol Rev 2005; 203:80-97

Akusjärvi G, Kreivi J-P, Petersen-Mahrt S. Messenger RNA in Eukaryotes. Encyclopedia of Life Sciences, e-Published 21 Dec 2007, doi: 10.1002/9780470015902.a0000875.pub2.

 


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