Selected Publications
Yamano H, Kitamura K, Kominami K, Lehmann A, Katayama S, Hunt T and Toda T. The spike of S-phase cyclin Cig2 expression at the G1-S border in fission yeast requires both APC and SCF ubiquitin ligases. Mol. Cell. 2000; 6: 1377-1387. PubMed
Kitamura K, Katayama S, Dhut S, Sato M, Watanabe Y, Yamamoto M and Toda T. Phosphorylation of Mei2 and Ste11 by Pat1 kinase inhibits sexual differentiation via ubiquitin proteolysis and 14-3-3 protein in fission yeast. Dev. Cell. 2001; 1: 389-399. PubMed
Garcia MA, Koonrugsa N and Toda T. Spindle-kinetochore attachment requires the combined action of Kin I-like Klp5/6 and Alp14/Dis1-MAPs in fission yeast. EMBO J. 2002; 21: 6015-6024. PubMed PDF (UKPMC)
Sato M, Vardy L, Garcia MA, Koonrugsa N, Toda T. Interdependency of fission yeast Alp14/TOG and coiled coil protein Alp7 in microtubule localization and bipolar spindle formation. Mol Biol Cell 2004; 15: 1609-1622. PubMed PDF (UKPMC)
Harrison C, Katayama S, Dhut S, Chen D, Jones N, Bähler J, Toda T. SCFPof1-ubiquitin and its target Zip2 transcription factor mediate cadmium response in fission yeast. EMBO J 2005; 24: 599-610. PubMed PDF (UKPMC)
Primary Research Publications
2009
Jourdain I, Spielewoy N, Thompson J, Dhut S, Yates Iii JR, Toda T. Identification of a conserved F-box protein 6 interactor essential for endocytosis cytokinesis in fission yeast. Biochem J. 2009 Feb 25.
Sato M, Okada N, Kakui Y, Yamamoto M, Yoshida M, Toda T. Nucleocytoplasmic transport of Alp7/TACC organizes spatiotemporal microtubule formation in fission yeast. EMBO Rep 2009 Aug 21.
Sato M, Toya M, Toda T. Visualization of Fluorescence-Tagged Proteins in Fission Yeast: The Analysis of Mitotic Spindle Dynamics Using GFP-Tubulin Under the Native Promoter. Methods Mol Biol. 2009;545:185-203.
2008
Griffiths K, Masuda H, Dhut S,Toda T. Fission yeast dam1-A8 mutant is resistant to and rescued by an anti-microtubule agent. Biochem Biophys Res Commun 2008;368(3):670-6
Unsworth A, Masuda H, Dhut S, Toda T. Fission Yeast Kinesin- 8 Klp5 and Klp6 Are Interdependent for Mitotic Nuclear Retention and Required for Proper Microtubule Dynamics. Mol Biol Cell 2008;19(12):5104-15
2007
Kearsey SE, Stevenson AL, Toda T, Wang SW. Fission yeast Cut8 is required for the repair of DNA double-strand breaks, ribosomal DNA maintenance, and cell survival in the absence of Rqh1 helicase. Mol Cell Biol 2007; 27(5):1558-1567
Kume K, Goshima T, Miyahara K, Toda T, Hirata D. A method for Pmo25-associated kinase assay in fission yeast: The activity is dependent on two GC kinases Nak1 and Sid1. Biosci Biotechnol Biochem 2007; 71(2 Spec Iss):615-617
Murakami H, Goto DB, Toda T, Chen ES, Grewal SI, Martienssen RA, Yanagida M. Ribonuclease activity of Dis3 is required for mitotic progression and provides a possible link between heterochromatin and kinetochore function. PLoS ONE 2007; 2(3):e317
Sato M, Toda T. Alp7/TACC is a crucial target in Ran-GTPase-dependent spindle formation in fission yeast. Nature 2007; 447(7142):334-U9
Toya M, Sato M, Haselmann U, Asakawa K, Brunner D, Antony C, Toda T. gamma-Tubulin complex-mediated anchoring of spindle microtubules to spindle-pole bodies requires Msd1 in fission yeast. Nat Cell Biol 2007; 9(6):646-U55
2006
Asakawa K, Kume K, Kanai M, Goshima T, Miyahara K, Dhut S, Tee WW, Hirata D, Toda T. The V260I mutation in fission yeast alpha-tubulin Atb2 affects microtubule dynamics and EB1-Mal3 localization and activates the Bub1 branch of the spindle checkpoint. Mol Biol Cell 2006; 17(3):1421-1435
Garcia I, Tajadura V, Martin V, Toda T, Sanchez Y. Synthesis of alpha-glucans in fission yeast spores is carried out by three alpha-glucan synthase paralogues, Mok12p, Mok13p and Mok14p. Mol Microbiol 2006; 59(3):836-853
Mamnun YM, Katayama S, Toda T. Fission yeast Mcl1 interacts with SCFPof3 and is required for centromere formation. Biochem Biophys Res Commun 2006; 350(1):125-130
Masuda H, Toda T, Miyamoto R, Haraguchi T, Hiraoka Y. Modulation of Alp4 function in Schizosaccharomyces pombe induces novel phenotypes that imply distinct functions for nuclear and cytoplasmic gamma-tubulin complexes. Genes Cells 2006; 11(4):319-336
Uritani M, Hidaka H, Hotta Y, Ueno M, Ushimaru T, Toda T. Fission yeast Tor2 links nitrogen signals to cell proliferation and acts downstream of the Rheb GTPase.. Genes Cells 2006; 11(12):1367-1379
2005
Asakawa K, Toya M, Sato M, Kanai M, Kume K, Goshima T, Garcia MA, Hirata D, Toda T. Mal3, the fission yeast EB1 homologue, cooperates with Bub1 spindle checkpoint to prevent monopolar attachment. EMBO Rep 2005; 6(12):1194-1200
Harrison C, Katayama S, Dhut S, Chen D, Jones N, Bahler J, Toda T. SCFPof1-ubiquitin and its target Zip1 transcription factor mediate cadmium response in fission yeast. EMBO J 2005; 24(3):599-610
Kanai M, Kume K, Miyahara K, Sakai K, Nakamura K, Leonhard K, Wiley DJ, Verde F, Toda T, Hirata D. Fission yeast MO25 protein is localized at SPB and septum and is essential for cell morphogenesis. EMBO J 2005; 24(17):3012-3025
Minoda A, Saitoh S, Takahashi K, Toda T. BAF53/Arp4 homolog Alp5 in fission yeast is required for histone H4 acetylation, kinetochore-spindle attachment, and gene silencing at centromere. Mol Biol Cell 2005; 16(1):316-327
Morishita T, Furukawa F, Sakaguchi C, Toda T, Carr AM, Iwasaki H, Shinagawa H. Role of the Schizosaccharomyces pombe F-box DNA helicase in processing recombination intermediates. Mol Cell Biol 2005; 25(18):8074-8083
Sanchez-Perez I, Renwick SJ, Crawley K, Karig I, Buck V, Meadows JC, Franco-Sanchez A, Fleig U, Toda T, Millar JBA. The DASH complex and Klp5/Klp6 kinesin coordinate bipolar chromosome attachment in fission yeast. EMBO J 2005; 24(16):2931-2943
Sato M, Dhut S, Toda T. New drug-resistant cassettes for gene disruption and epitope tagging in Schizosaccharomyces pombe. Yeast 2005; 22(7):583-591
Wang SW, Asakawa K, Win TZ, Toda T, Norbury CJ. Inactivation of the pre-mRNA cleavage and polyadenylation factor Pfs2 in fission yeast causes lethal cell cycle defects. Mol Cell Biol 2005; 25(6):2288-2296
Wee S, Geyer RK, Toda T, Wolf DA. CSN facilitates Cullin-RING ubiquitin ligase function by counteracting autocatalytic adapter instability. Nat Cell Biol 2005; 7(4):387-391
Yamashita A, Sato M, Fujita A, Yamamoto M, Toda T. The roles of fission yeast Ase1 in mitotic cell division, meiotic nuclear oscillation, and cytokinesis checkpoint signaling. Mol Biol Cell 2005; 16(3):1378-1395
2004
Lehmann A, Katayama S, Harrison C, Dhut S, Kitamura K, McDonald N, Toda T. Molecular interactions of fission yeast Skp1 and its role in the DNA damage checkpoint. Genes Cells 2004; 9(5):367-382
Lehmann A, Toda T. Fission yeast Skp1 is required for spindle morphology and nuclear membrane segregation at anaphase. FEBS Lett 2004; 566(1-3):77-82
Sato M, Vardy L, Garcia MA, Koonrugsa N, Toda T. Interdependency of fission yeast Alp14/T0G and coiled coil protein Alp7 in microtubule localization and bipolar spindle formation. Mol Biol Cell 2004; 15(4):1609-1622
Tange Y, Fujita A, Toda T, Niwa O. Functional dissection of the gamma-tubulin complex by suppressor analysis of gth1 and alp4 mutations in Schizosaccharomyces pombe. Genetics 2004; 167(3):1095-1107
Yamano H, Kominami K, Harrison C, Kitamura K, Katayama S, Dhut S, Hunt T, Toda T. Requirement of the SCFPop1/Pop2 ubiquitin ligase for degradation of the fission yeast S phase cyclin Cig2. J Biol Chem 2004; 279(18):18974-18980
2003
Hafezparast M, Klocke R, Ruhrberg C, Marquardt A, Ahmad-Annuar A, Bowen S, Lalli G, Witherden AS, Hummerich H, Nicholson S, Morgan PJ, Oozageer R, Priestley JV, Averill S, King VR, Ball S, Peters J, Toda T, Yamamoto A, Hiraoka Y, Augustin M, Korthaus D, Wattler S, Wabnitz P, Dickneite C, Lampel S, Boehme F, Peraus G, Popp A, Rudelius M, Schlegel J, Fuchs H, de Angelis MH, Schiavo G, Shima DT, Russ AP, Stumm G, Martin JE, Fisher EMC Mutations in dynein link motor neuron degeneration to defects in retrograde transport. Science 2003; 300(5620):808-812
Konomi M, Fujimoto K, Toda T, Osumi M. Characterization and behaviour of alpha-glucan synthase in Schizosaccharomyces pombe as revealed by electron microscopy. Yeast 2003; 20(5):427-438
Sato M, Koonrugsa N, Toda T, Vardy L, Tournier S, Millar JBA. Deletion of Mia1/Alp7 activates Mad2-dependent spindle assembly checkpoint in fission yeast. Nat Cell Biol 2003; 5(9):764-766
2002
Fujita A, Vardy L, Garcia MA, Toda T. A fourth component of the fission yeast gamma-tubulin complex, Alp16, is required for cytoplasmic microtubule integrity and becomes indispensable when gamma-tubulin function is compromised. Mol Biol Cell 2002; 13(7):2360-2373
Garcia MA, Koonrugsa N, Toda T. Spindle-kinetochore attachment requires the combined action of Kin I-like KIp5/6 and AIp14/Dis1-MAPs in fission yeast. EMBO J 2002; 21(22):6015-6024
Garcia MA, Koonrugsa N, Toda T. Two kinesin-like Kin I family proteins in fission yeast regulate of metaphase and the on the establishment set of anaphase A. Curr Biol 2002; 12(8):610-621
Hirata D, Kishimoto N, Suda M, Sogabe Y, Nakagawa S, Yoshida Y, Sakai K, Mizunuma M, Miyakawa T, Ishiguro J, Toda T. Fission yeast Mor2/Cps12, a protein similar to Drosophila Furry, is essential for cell morphogenesis and its mutation induces Wee1-dependent G(2) delay. EMBO J 2002; 21(18):4863-4874
Ikebe C, Kominami K, Toda T, Nakayama K-I. Isolation and characterization of a novel F-box protein Pof-10 in fission yeast. Biochem Biophys Res Commun 2002; 290(5):1399-1407
Katayama S, Kitamura K, Lehmann A, Nikaido O, Toda T. Fission yeast F-box protein Pof3 is required for genome integrity and telomere function. Mol Biol Cell 2002; 13(1):211-224
Vardy L, Fujita A, Toda T. The gamma-tubulin complex protein Alp4 provides a link between the metaphase checkpoint and cytokinesis in fission yeast. Genes Cells 2002; 7(4):365-373
Other Publications
Sato M,Toya M,Toda T. Is spindle formation in fission yeast specific to the species?: from the viewpoint of nuclear transport and spindle pole body. Tanpakushitsu Kakusan Koso 2008;53(3):197-206
Asakawa K, Toda T. Cooperation of EB1-Mal3 and the Bub1 spindle checkpoint. Cell Cycle 2006; 5(1):27-30
Horio T, Toda T. Organizing cytoplasmic microtubules: no nucleus, no problem. Nat Cell Biol 2006; 8(10):1041-1043
Matsuo Y, Asakawa K, Toda T, Katayama S. A rapid method for protein extraction from fission yeast. Biosci Biotechnol Biochem 2006; 70(8):1992-1994
Sato M, Toda T. Reconstruction of microtubules: entry into interphase. Dev Cell 2004; 6(4):456-458
