Selected Publications

Wendler F, Page L, Urbé S and Tooze SA. Homotypic fusion of immature secretory granules during maturation requires syntaxin 6. Mol Biol Cell 2001; 12: 1699-1709. PubMed PDF (UKPMC)

Hinners I, Wendler F, Fei H, Thomas L, Thomas G and Tooze SA. AP-1 recruitment to VAMP4 is modulated by phosphorylation-dependent binding of PACS-1. EMBO Reports 2003; 4: 1182-1189. PubMed PDF (UKPMC)

Köchl R, Hu XW, Chan EYW and Tooze SA. Microtubules facilitate autophagosome formation and fusion of autophagosomes with endosomes. Traffic 2006; 7: 129-145. PubMed

Kakhlon O, Sakya P, Larijani B, Watson R and Tooze SA. GGA function is required for maturation of neuroendocrine secretory granules. EMBO J 2006; 25: 1590-1602. PubMed PDF (UKPMC)

Ahras M, Otto GP and Tooze SA. Synaptotagmin IV is necessary for the maturation of secretory granules in PC12 cells. J Cell Biol 2006; 173: 241-251. PubMed PDF (UKPMC)

Primary Research Publications

2009

Chan EY, Tooze SA. Evolution of Atg1 function and regulation. Autophagy 2009 Aug;5(6):758-65.

Longatti A, Tooze SA. Vesicular trafficking and autophagosome formation. Cell Death Differ. 2009 Apr 17.

Morvan J, Köchl R, Watson R, Collinson LM, Jefferies HB, Tooze SA. In vitro reconstitution of fusion between immature autophagosomes and endosomes. Autophagy 2009 Jul;5(5):676-89.

Razi M, Chan EY, Tooze SA. Early endosomes and endosomal coatomer are required for autophagy. J Cell Biol. 2009 Apr 20;185(2):305-21.

Razi M, Tooze SA. Correlative light and electron microscopy. Methods Enzymol. 2009;452:261-75.

2008

Chan EY, Longatti A, McKnight NC, Tooze SA. Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domain using an Atg13-independent mechanism. Molecular Cellular Biology 2008;doi:10.1128/MCB.01082-08

2007

Chan EYW, Kir S, Tooze SA. SiRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy. J Biol Chem 2007; 282(35):25464-25474

Webber JL, Young ARJ, Tooze SA. Atg9 trafficking in mammalian cells. Autophagy 2007; 3(1):54-56

2006

Ahras M, Otto GP, Tooze SA. Synaptotagmin IV is necessary for the maturation of secretory granules in PC12 cells. J Cell Biol 2006; 173(2):241-251

Kakhlon O, Sakya P, Larijani B, Watson R, Tooze SA. GGA function is required for maturation of neuroendocrine secretory granules. EMBO J 2006; 25(8):1590-1602

Kochl R, Hu XW, Chan EYW, Tooze SA. Microtubules facilitate autophagosome formation and fusion of autophagosomes with endosomes. Traffic 2006; 7(2):129-145

Young ARJ, Chan EYW, Hu XW, Kochl R, Crawshaw SG, High S, Hailey DW, Lippincott-Schwartz J, Tooze SA. Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes. J Cell Sci 2006; 119(18):3888-3900

2003

Alberts P, Rudge R, Hinners I, Muzerelle A, Martinez-Arca S, Irinopoulou T, Marthiens V, Tooze S, Rathjen F, Gaspar P, Galli T. Cross talk between tetanus neurotoxin-insensitive vesicle-associated membrane protein-mediated transport and L1-mediated adhesion. Mol Biol Cell 2003; 14(10):4207-4220

Hinners I, Wendler F, Fei H, Thomas L, Thomas G, Tooze SA. AP-1 recruitment to VAMP4 is modulated by phosphorylation-dependent binding of PACS-1. EMBO Rep 2003; 4(12):1182-1189

2002

Austin C, Boehm M, Tooze SA. Site-specific cross-linking reveals a differential direct interaction of class 1, 2, and 3 ADP-ribosylation factors with adaptor protein complexes 1 and 3. Biochemistry 2002; 41(14):4669-4677

Panaretou C, Tooze SA. Regulation and recruitment of phosphatidylinositol 4-kinase on immature secretory granules is independent of ADP-ribosylation factor 1. Biochem J 2002; 363(Pt 2):289-295

Other Publications

de Lartigue J, Polson H, Feldman M, Shokat K, Tooze SA, Urbé S, Clague MJ. PIKfyve regulation of endosome-linked pathways. Traffic 2009 Jul;10(7):883-93

Klionsky, DJ (195 authors),Tooze, SA, (25 authors), Deter, RL. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 2008;4(2):151-75

Morvan J, Tooze SA. Discovery and progress in our understanding of the regulated secretory pathway in neuroendocrine cells. Histochem Cell Biol 2008;129(3):243-252

Tooze SA, Schiavo G. Liaisons dangereuses: autophagy, neuronal survival and neurodegeneration. Curr Opin Neurobiol 2008;18(5):504-15

Young A, Tooze SA. Protein Trafficking into Autophagosomes. Methods in Molecular Biology 2008;445(5):147-157

Hinners I, Tooze SA. Changing directions: clathrin-mediated transport between the Golgi and endosomes. J Cell Sci 2003; 116(5):763-771