Selected Publications
Marples B, Scott SD, Hendry JH, Embleton MJ, Lashford LS and Margison GP. Development of synthetic promoters for radiation-mediated gene therapy. Gene Ther 2000; 7: 511-517.
Scott SD, Marples B, Hendry JH, Lashford LS, Embleton MJ, Humter RD, Howell A and Margison GP. A radiation-controlled molecular switch for use in gene therapy of cancer. Gene Ther 2000; 7: 1121-1125.
Shaw DM, Embleton MJ, Westwater C, Ryan MG, Myers KA, Kingsman SM, Carroll MW and Stern PL. Isolation of a high affinity scFv from a monoclonal antibody recognising the oncofoetal antigen 5T4. Biochim Biophys Acta 2000; 1524: 238-246.
Seedhouse CH, Margison GP, Hendry JH, Hajeer A and Embleton MJ. Anti8-ore-2 '-deoxyguanosine phage antibodies: isolation, characterization and relationship to disease states. Biochem Biophys Res Comm 2001; 280: 595-604.
Ray K, Embleton MJ, Jailkhani BL, Bhan MK and Kumar R. Selection of single chain variable fragments (scFv) against the glycoprotein antigen of the rabies virus from a human synthetic phage display library, and their fusion with the Fc region of human IgG1. Clin Exp Immunol 2001; 125: 94-101.
Dehal PK, Embleton MJ, Kemshead JT and Hawkins RE. Targeted cytokine delivery to neuroblastoma. Biochem Soc Trans 2002; 30: 518-520.
Myers KA, Ryan MG, Stern PL, Shaw DM, Embleton MJ, Kingsman SM and Carroll MW. Targeting immune effector molecules to human tumor cells via 5T4-specific scFv fusion proteins. Cancer Gene Therapy 2002; 9: 884-896.