Key Publications
2008
O'Connor JPB, Jackson A, Asselin M-C, Buckely DL, Parker GJM, Jayson GC. Quantitative image biomarkers in the clinical development of targeted therapeutics: current and future perspectives. Lancet Oncology; in press.
Roberts C, Parker GJM, Watson Y, Rose CJ, O'Connor JP, Stivaros S, Jackson A, Rushton VE. The Use of DCE-MRI and Pharmacokinetic Modelling in the Assessment of Glandular Function in Sjögren's Syndrome. Radiology 2008; 246: 845-853.
McGrath DM, Naish JN, O'Connor JPB, Hutchinson CE, Waterton JC, Taylor CJ, Parker GJM. Oxygen-Induced Changes in Longitudinal Relaxation Times in Skeletal Muscle. Magn Res Imag 2008; 26: 221-227.
2007
O'Connor JPB, Jayson GC, Jackson A, Ghiorghiu D, Carrington BM, Mills SJ, Rose CJ, Swindell R, Roberts C, Mitchell CL, Parker GJM. Enhancing fraction predicts clinical outcome following first line chemotherapy in patients with epithelial ovarian carcinoma. Clinical Can Res 2007; 13: 6130-6135.
O'Connor JPB, Jackson A, Buonaccorsi GA, Buckley DL, Roberts C, Watson Y, Cheung S, McGrath DM, Naish JN, Rose CJ, Dark PM, Jayson GC, Parker GJM. Organ-specific effects of oxygen and carbogen gas inhalation on tissue longitudinal relaxation times. Magn Res Med 2007; 58: 490-496.
Buonaccorsi GA, O'Connor JP, Caunce A, Roberts C, Cheung S, Watson Y, Davies K, Jackson A, Jayson GC, Parker GJ. Tracer kinetic model driven registration for DCE-MRI time-series data: methodology and initial validation in software phantoms and patient data. Magn Res Med 2007; 58: 1010-1019.
O'Connor JPB, Jackson A, Parker GJ, Jayson GC. DCE-MRI biomarkers in the clinical evaluation of antiangiogenic and vascular disrupting agents. Br J Cancer 2007; 96: 189-95.
Rose CJ, Mills SJ, O'Connor JPB, Buonaccorsi GA, Roberts C, Watson Y, Whitcher B, Jayson GC, Jackson A, Parker GJM. Quantifying Heterogeneity in Dynamic Contrast-Enhanced MRI Parameter Maps. Lecture Notes Comp Sci 2007; 4792: 376-384.
Jackson A, O'Connor JP, Parker GJ, Jayson GC. Imaging tumor vascular heterogeneity and angiogenesis using DCE-MRI. Clinical Can Res 2007; 13: 3449-3459.
O'Connor JPB, Rosa DD, Jackson A, Jayson GC. Molecular imaging of targets and therapeutics in tumour angiogenesis. In: Marmé D, Fusenig N (ed.) Tumor Angiogenesis: Basic Mechanisms and Cancer Therapy. New York: Springer, 2007. ISBN: 978-3-540-33176-6. Chapter 29 pp 511-528.
2006
Buonaccorsi GA, Roberts C, Cheung S, Watson Y, O'Connor JP, Davies K, Jackson A, Jayson GC and Parker GJ. Comparison of the performance of tracer kinetic model-driven registration for dynamic contrast enhanced MRI using different models of contrast enhancement. Acad Radiol 2006; 13: 1112-1123.
