Selected Publications
C. J. Moody and E. Swann, Novel Bioreductive
Anticancer Agents Based on Indolequinones.
Farmaco, 1997, 52, 271-279.
M. A. Naylor, E. Swann, S. A. Everett, M. Jaffar, J. Nolan, N. Robertson,
S. D. Lockyer, K. B. Patel, M. F. Dennis, M. R. L. Stratford, P. Wardman,
G. E. Adams, C. J. Moody, and I. J. Stratford, Indolequinone Anti-tumor
Agents: Reductive Activation and Elimination from (5-Methoxy-1,2-dimethyl-4,7-dioxo-indol-3-yl)methyl
Derivatives and Hypoxia-Selective Cytotoxicity in vitro.
J. Med. Chem., 1998, 41, 2720-2731.
H. D. Beall, S. Winski, E. Swann, A. R. Hudnott, A. S. Cotterill, N.
O'Sullivan, S. J. Green, R. Bien, D. Siegel, D. Ross, and C. J. Moody,
Indolequinone Antitumor Agents: Correlation between Quinone Structure,
Rate of Metabolism by Recombinant Human NQO1 and in vitro Cytotoxicity.
J. Med. Chem., 1998, 41, 4755-4766.
S. A. Everett, M. A. Naylor, P. Barraja, E. Swann, K. B. Patel, M.
R. L. Stratford, A. R. Hudnott, B. Vojnovic, R. J. Locke, P. Wardman,
and C. J. Moody,
Controlling the rates of reductively activated elimination from the (indol'3'yl)methyl
position of indolequinones.
J. Chem. Soc., Perkin Trans. 2, 2001, 843-860.
M. Faig, M. A. Bianchet, S. Winski, R. Hargreaves, C. J. Moody, A.
R. Hudnott, D. Ross, and L. M. Amzel,
Structure-based development of anticancer drugs: Complexes of NAD(P)H:quinone
oxidoreductase 1 with chemotherapeutic quinones.
Structure, 2001, 9, 659-667.