Selected Publications
Playford MP, Bicknell D, Bodmer WF, Macaulay VM.
Insulin-like growth factor 1 regulates the location, stability and transcriptional
activity of beta-catenin. Proc Natl Acad Sci USA 97:12103-12108,
2000
Macaulay VM, Salisbury AJ, Bohula EA, Playford MP, Smorodinsky NI,
Shiloh Y.
Antisense-mediated downregulation of the type 1 IGF receptor in mouse
melanoma cells is associated with enhanced radiosensitivity and impaired
activation of Atm kinase. Oncogene 20: 4029-4040, 2001.
Hassan AB, Macaulay VM
The Insulin-like growth factor system as a therapeutic target in colorectal
cancer.
Annals of Oncology, in press
GO Hellawell, GDH Turner, DR Davies, R Poulsom, SF. Brewster and VM
Macaulay
Expression of the type 1 insulin-like growth factor receptor is upregulated
in primary prostate cancer and commonly persists in metastatic disease.
Submitted to Cancer Research