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University of Oxford
Len Seymour
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Publications

Selected Publications

Fisher, K.D., Stallwood, Y., Mautner, V., Ulbrich, K., Etrych, T., Strohalm, J. and Seymour, L.W., Polymer-coated adenovirus permits efficient retargeting and evades neutralising antibody, Gene Therapy 8, 341-348 (2001).

Oupicky, D., Parker, A.L., Seymour, L.W., Use of a reducible trigger mechanism for intracellular activation of polyelectrolyte gene delivery systems capable of extended plasma circulation, J. American Chemical Soc., 124 (1) 8-9 (2002).

Ogris, M. , Carlisle, R.C., Bettinger, T. and Seymour, L.W., Melittin enables efficient vesicular escape and enhanced nuclear access of non-viral gene delivery vectors, J. Biological Chemistry, 276, 47550-47555 (2001).

Bettinger, T., Carlisle, R.C., Read, M.L. and Seymour, L.W. Peptide-mediated RNA delivery: A novel approach for enhanced transfection of primary and post mitotic cells, Nucleic Acids Research, 29 (18) 1-10 (2001).

Carlisle, R.C., Bettinger, T., Ogris, M., Smart, S., Mautner, V. and Seymour, L.W. Adenovirus hexon protein enhances nuclear delivery and increases transgene expression using polyethyleneimine/plasmid DNA vectors, Molecular Therapy, 4, 473-483 (2001).
 


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