Selected Publications
Watt PM, Louis EJ, Borts RH and Hickson ID. Sgs1: a eukaryotic homolog of E. coli RecQ that interacts with topoisomerase II in vivo and is required for faithful chromosome segregation. Cell 1995; 81: 253-260.
Karow JK, Constantinou A, Li J-L, West SC and Hickson ID. The Bloom's syndrome gene product promotes branch migration of Holliday junctions. Proc Natl Acad Sci USA 2000; 97: 6504-6508.
Chakraverty RK, Kearsey JM, Oakley TJ, Grenon M, de la Torre Ruiz M-A, Lowndes NF and Hickson ID. Topoisomerase III acts upstream of Rad53p in the S-phase DNA damage checkpoint. Mol Cell Biol 2001; 21: 7150-7162.
Hickson ID. RecQ helicases: caretakers of the genome. Nature Reviews Cancer 2003; 3: 169-178.
Wu L and Hickson ID. The Bloom's syndrome helicase suppresses crossing over during homologous recombination. Nature 2003; 426: 870-874.
Wu L, Chan KL, Ralf C, Bernstein DA, Garcia PL, Bohr VA, Vindigni A, Janscak P, Keck JL and Hickson ID. The HRDC domain of BLM is required for the dissolution of double Holliday junctions. EMBO Journal 2005; 24: 2679-2687.