Steven Lee
University of Birmingham
Vincent Drive
Edgbaston
Birmingham
B15 2TT
United Kingdom
Email: s.p.lee@bham.ac.uk
Tel: 0121 414 2803
Web: Lab website
Scientific summary
Antibodies for cancer therapy are already in clinical use, but T cells offer even greater potential in this context because of their ability to recognise intracellular antigens. Dr Lee's laboratory is seeking to develop T cell therapy for human cancer by focussing on those tumours that carry the Epstein-Barr virus (EBV), a known target for the T cell response.
Steven Lee other research projects
Senior Cancer Research Fellowship
Funding period: 01 February 2006 to 31 January 2012
Funding period: 01 February 2006 to 31 January 2012
Recent publications
Expression of the Epstein-Barr virus-encoded Epstein-Barr virus nuclear antigen 1 in Hodgkin's lymphoma cells mediates up-regulation of CCL20 and the migration of regulatory T cells
Am J Pathol.2008;173 :195-204
CD4(+) T-cell responses to Epstein-Barr virus (EBV) latent-cycle antigens and the recognition of EBV-transformed lymphoblastoid cell lines
J Virol.2005;79 :4896-4907
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