Tony Carr
University of Sussex
Sussex House
Southern Ring Road
Falmer
Brighton
BN1 9RH
United Kingdom
Email: a.m.carr@sussex.ac.uk
Tel: 01273 678123
Web: Lab website
Scientific summary
The checkpoint kinase ATR is key for maintaining genome integrity, functioning during replication to coordinate the response to endogenous and exogenous replication perturbation. These responses are important cancer avoidance pathways and are vital to the response to therapeutic agents.
Recent publications
Regulation of ribonucleotide reductase by Spd1 involves multiple mechanisms
Genes Dev.2010;24 :1145-1159
Replication fork arrest, recombination and the maintenance of ribosomal DNA stability
DNA Repair (Amst).2008;7 :1613-1623
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