David Lane
University of Dundee
College of Life Sciences
Dow Street
Dundee
DD1 5EH
United Kingdom
Email: d.p.lane@dundee.ac.uk
About David Lane
Professor Sir David Lane is one of the world's leading cancer researchers, and was Cancer Research UK's first Chief Scientist from 2007 until 2010. His work has been funded by the charity for more than 30 years, and in 1979 he discovered the p53 protein, which plays a central role in preventing cancer. He and his team are now investigating ways to turn our knowledge about the molecules involved in cancer - including p53 - into life-saving treatments for the disease. Professor Lane has won many international prizes and awards for his outstanding work in this field.
David Lane other research projects
Funding period: 01 January 2007 to 31 December 2012
Biological Sciences Committee (BSC) Programme Grants
Funding period: 01 October 2008 to 31 December 2012
Recent publications
p53 isoforms Delta 133p53 and p53 beta are endogenous regulators of replicative cellular senescence
Nat Cell Biol.2009;11 :1135-1142
p53 isoform Delta 113p53 is a p53 target gene that antagonizes p53 apoptotic activity via BclxL activation in zebrafish
Genes Dev.2009;23 :278-290
