Reuben Tooze
University of Leeds
Woodhouse Lane
Leeds
LS2 9JT
United Kingdom
Scientific summary
The goal of Dr Tooze and his group is to generate a detailed understanding of the changes in gene regulatory networks occurring during terminal differentiation of human B-cells. They are interested in how these networks are affected by the cellular micro-environment and how these networks relate to phenotypes of B-cell malignancies.
Recent publications
An extended set of PRDM1/BLIMP1 target genes links binding motif type to dynamic repression
Nucleic Acids Res.2010;38 :5336-5350
