Mahvash Tavassoli
King's College London
Strand
London
WC2R 2LS
United Kingdom
Scientific summary
Apoptin, a small protein derived from chicken anemia virus has the ability to induce cell death in cancer cells while leaving normal cells unharmed. In normal cells the protein is localised in the cytoplasm while in cancer cells it is translocated to the nucleus.
Recent publications
p400 function is required for the adenovirus E1A-mediated suppression of EGFR and tumour cell killing
Oncogene.2007;26 :6863-6874
Crucial Roles for Protein Kinase C Isoforms in Tumor-Specific Killing by Apoptin
Cancer Res.2010;70 :7242-7252
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