Alan Storey

Researcher Alan Storey
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University of Oxford
Weatherall Institute of Molecular Medicine
John Radcliffe Hospital
Oxford
OX3 9DS
United Kingdom

Email: alan.storey@imm.ox.ac.uk
Tel: 01865 222407
Web: Lab website

Professor Alan Storey leads the HPV Apoptosis and Cancer Group at the Weatherall Institute of Molecular Medicine. His research focuses on non-melanoma skin cancer (NMSC), the most commonly diagnosed cancer in the UK. Although NMSC is rarely life-threatening, it is estimated that there are at least 100,000 cases in the UK each year making it a significant public health problem. Professor Storey's team is investigating how human papillomavirus (HPV) infection of the skin can contribute to the development of this disease.

Apoptosis, or programmed cell death, is a highly controlled cellular process essential for homeostasis. Evasion of apoptosis is a hallmark trait of cancer development and one of the major obstacles to effective treatments.

Recent publications


Tyrosine dephosphorylation is required for Bak activation in apoptosis

EMBO J.2010;29 :3853-3868

Cutaneous HPV5 E6 causes increased expression of Osteoprotegerin and Interleukin 6 which contribute to evasion of UV-induced apoptosis

Carcinogenesis.2010;31 :2155-2164